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Title: Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process
Authors: Ronald Grigg
Tossapol Khamnaen
Shuleewan Rajviroongit
Visuvanathar Sridharan
University of Leeds
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Apr-2002
Citation: Tetrahedron Letters. Vol.43, No.14 (2002), 2601-2603
Abstract: A novel palladium-catalysed three-component cascade process involving 2-iodobenzoyl chloride or methyl 2-iodobenzoate, allene and primary aliphatic or aromatic amines furnishes N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones in good yield. © 2002 Elsevier Science Ltd. All rights reserved.
ISSN: 00404039
Appears in Collections:Scopus 2001-2005

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