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Title: Evaluation of antimycobacterial, antiplasmodial and cytotoxic activities of preussomerins isolated from the lichenicolous fungus Microsphaeropsis sp. BCC 3050
Authors: Prapairat Seephonkai
Masahiko Isaka
Prasat Kittakoop
Prasit Palittapongarnpim
Sumalee Kamchonwongpaisan
Morakot Tanticharoen
Yodhathai Thebtaranonth
Mahidol University
Thailand National Center for Genetic Engineering and Biotechnology
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Medicine;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 11-Feb-2002
Citation: Planta Medica. Vol.68, No.1 (2002), 45-48
Abstract: A new preussomerin isomer, 3′-O-demethylpreussomerin I, five known preussomerins E-I, and two known deoxypreussomerins, deoxypreussomerin A and bipendensin (palmarumycin C11), were isolated from a lichenicolous fungus Microsphaeropsis sp. BCC 3050. These structures were elucidated by spectroscopic methods, especially 1D- and 2D-NMR. The preussomerins were evaluated for their antimycobacterial and antiplasmodial activities as well as cytotoxicity against KB, BC-1 and vero cell lines.
ISSN: 00320943
Appears in Collections:Scopus 2001-2005

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