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Title: Two new pyranoflavanones from the stems of Derris reticulata
Authors: Chulabhorn Mahidol
Hunsa Prawat
Wirongrong Kaweetripob
Somsak Ruchirawat
Chulabhorn Research Institute
The Institute of Science and Technology for Research and Development, Mahidol University
Mahidol University
Keywords: Chemistry;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 1-Jul-2002
Citation: Heterocycles. Vol.57, No.7 (2002), 1287-1292
Abstract: Two new flavonoids, 4′,5-dihydroxy-8-hydroxymethyl-6″,6″- dimethylpyrano[2′,3′:7,6]flavanone (1), and 2′,3′-dihydroxylupinifolin (2) were isolated from the stems of Derris reticulata. Both compounds showed cytotoxic activity in the P-388 cell line. The structures were established by spectroscopic analysis and chemical transformations. The biosynthetic origin and the mechanism of formation of the hydroxymethyl group in compound (1) are proposed.
ISSN: 03855414
Appears in Collections:Scopus 2001-2005

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