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|Title:||Two new pyranoflavanones from the stems of Derris reticulata|
Chulabhorn Research Institute
The Institute of Science and Technology for Research and Development, Mahidol University
|Keywords:||Chemistry;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Heterocycles. Vol.57, No.7 (2002), 1287-1292|
|Abstract:||Two new flavonoids, 4′,5-dihydroxy-8-hydroxymethyl-6″,6″- dimethylpyrano[2′,3′:7,6]flavanone (1), and 2′,3′-dihydroxylupinifolin (2) were isolated from the stems of Derris reticulata. Both compounds showed cytotoxic activity in the P-388 cell line. The structures were established by spectroscopic analysis and chemical transformations. The biosynthetic origin and the mechanism of formation of the hydroxymethyl group in compound (1) are proposed.|
|Appears in Collections:||Scopus 2001-2005|
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