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Title: Estimation of plasma insulin from plasma glucose
Authors: Chatchai Neatpisarnvanit
John Robert Boston
Mahidol University
University of Pittsburgh
Keywords: Engineering
Issue Date: 1-Nov-2002
Citation: IEEE Transactions on Biomedical Engineering. Vol.49, No.11 (2002), 1253-1259
Abstract: Two plasma insulin estimators are derived and evaluated in this paper. The estimators use continuously monitored plasma glucose, and they are based on a simple mathematical model of glucose-insulin metabolism. The first estimator (Estimator 1) was obtained from the glucose subsystem of the simplified model, which includes plasma glucose and interstitial insulin compartments. The second estimator (Estimator 2) was developed from the insulin kinetics subsystem of the simplified model. The performances of the estimators were compared using computer simulations and data from clinical intravenous glucose tolerance test procedures and from animal experiments.
ISSN: 00189294
Appears in Collections:Scopus 2001-2005

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