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dc.contributor.authorM. Nacheren_US
dc.contributor.authorP. Singhasivanonen_US
dc.contributor.authorS. Treeprasertsuken_US
dc.contributor.authorS. Vannaphanen_US
dc.contributor.authorB. Traoreen_US
dc.contributor.authorS. Looareesuwanen_US
dc.contributor.authorF. Gayen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-07-24T03:01:37Z-
dc.date.available2018-07-24T03:01:37Z-
dc.date.issued2002-01-01en_US
dc.identifier.citationAnnals of Tropical Medicine and Parasitology. Vol.96, No.1 (2002), 5-13en_US
dc.identifier.issn00034983en_US
dc.identifier.other2-s2.0-0036105109en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036105109&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/20230-
dc.description.abstractAlthough human infection with Ascaris appears to be associated with protection from cerebral malaria, there are many potential socio-economic and nutritional confounders related to helminth infection that need to be considered. In a hospital-based study, 37 cases of cerebral malaria and 61 cases of non-severe malaria with high parasite biomass (i.e. hyperparasitaemia and/or circulating schizonts) answered a structured questionnaire and were screened for intestinal helminths. Logistic regression was then used to adjust for the potential confounders. The adjusted odds ratios (OR) and their 95% confidence intervals (CT) still showed a significant protective association for helminths (OR = 0.24; CI = 0.07-0.78; P= 0.02) and malnutrition (OR = 0.11; CI = 0.02-0.58; P= 0.01), with no evidence of interaction between the two. There was also a significant dose-effect trend for the helminth infections (P= 0.048). These results, despite coming from a hospital-based study, indicate that the apparent association between helminths and protection from cerebral malaria is not the result of socio-economic or nutritional confounders.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036105109&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleIntestinal helminths and malnutrition are independently associated with protection from cerebral malaria in Thailanden_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1179/000349802125000448en_US
Appears in Collections:Scopus 2001-2005

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