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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/20462
Title: Baseline levels of plasma endothelin-1 (ET-1) and changes during transfusion in thalassemic patients
Authors: Vip Viprakasit
Suthida Kankirawatana
Pravit Akarasereenont
Kritvikrom Durongpisitkul
Sirikul Chotewuttakorn
Voravarn S. Tanphaichitr
Weatherall Institute of Molecular Medicine
Mahidol University
John Radcliffe Hospital
University of Oxford
Keywords: Medicine
Issue Date: 4-Jul-2002
Citation: American Journal of Hematology. Vol.70, No.3 (2002), 260-262
Abstract: We studied levels of plasma endothelin-1 (ET-1) in 25 β-thalassemia/Hb E patients before and after blood transfusion. Baseline ET-1 levels in these patients were significantly higher than in normal controls (10.17 ± 2.1 pg/mL vs. 8.9 ± 2.0 pg/mL, P < 0.05). After blood transfusion, levels of plasma ET-1 tend to slightly increase during the first 24 hr but significantly decline at the 7thday to levels (8.01 ± 1.7 pg/mL) which do not differ from those of controls. This study highlights a different alteration of plasma ET-1 in patients with β-thalassemia compared to that of patients with sickle-cell anemia. © 2002 Wiley-Liss, Inc.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0036089573&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/20462
ISSN: 03618609
Appears in Collections:Scopus 2001-2005

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