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|Title:||Comparison of oral artesunate and dihydroartemisinin antimalarial bioavailabilities in acute falciparum malaria|
|Authors:||Paul N. Newton|
Michele Van Vugt
Nicholas J. White
|Keywords:||Medicine;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Antimicrobial Agents and Chemotherapy. Vol.46, No.4 (2002), 1125-1127|
|Abstract:||Plasma antimalarial activity following oral artesunate or dihydroartemisinin (DHA) treatment was measured by a bioassay in 18 patients with uncomplicated faiciparum malaria. The mean antimalarial activity in terms of the bioavailability of DHA relative to that of artesunate did not differ significantly from 1, suggesting that DHA can be formulated to be an acceptable oral alternative to artesunate.|
|Appears in Collections:||Scopus 2001-2005|
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