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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/20762
Title: Further developments in the synthesis of lamellarin alkaloids via direct metal-halogen exchange
Authors: Poonsakdi Ploypradith
Wiyada Jinaglueng
Chitkavee Pavaro
Somsak Ruchirawat
Chulabhorn Research Institute
Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry;Pharmacology, Toxicology and Pharmaceutics
Issue Date: 10-Feb-2003
Citation: Tetrahedron Letters. Vol.44, No.7 (2003), 1363-1366
Abstract: Direct metal-halogen exchange of 2-bromopyrrole carbonate derivatives with tert-butyllithium followed by the intramolecular lactonization of the resulting 2-pyrrole anion onto the carbonate provided the corresponding lamellarins in moderate to good yield. The lamellarin framework could be obtained from the direct metal-halogen exchange strategy in a 26-33% overall yield over 5-6 steps. © 2003 Elsevier Science Ltd. All rights reserved.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0037429073&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/20762
ISSN: 00404039
Appears in Collections:Scopus 2001-2005

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