Please use this identifier to cite or link to this item:
|Title:||Monitoring of Plasmodium vivax sensitivity to chloroquine in vitro in Thailand|
Hormozgan University of Medical Sciences
|Keywords:||Immunology and Microbiology|
|Citation:||Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.97, No.4 (2003), 435-437|
|Abstract:||The sensitivity of Plasmodium vivax to chloroquine in vitro was investigated in patients admitted to the Bangkok Hospital for Tropical Diseases, Thailand, between September 2001 and May 2002. Of 42 isolates, 34 were successfully tested for parasite sensitivity to chloroquine in vitro; the results showed a significant decrease in sensitivity compared with data published in 1989 and 1995: the IC50and IC90were 187.2 and 1217.9 ng/mL blood, respectively, an approximate 4-fold decrease in sensitivity in comparison with other data from the past 2 decades. A number of in vitro tests were performed simultaneously using both WHO microplates and our own laboratory-prepared pre-dosed microplates under the same conditions and there was no significant difference between the results.|
|Appears in Collections:||Scopus 2001-2005|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.