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|Title:||Relationship of tobacco smoking with serum vitamin B<inf>12</inf>, folic acid and haematological indices in healthy adults|
Frank Peter Schelp
Freie Universitat Berlin
|Citation:||Public Health Nutrition. Vol.6, No.7 (2003), 675-681|
|Abstract:||Objectives: To investigate the effects of tobacco smoking on serum vitamin B12, folic acid and haematological parameters in healthy Thai smokers and non-smokers. Design: Cross-sectional study of smokers and non-smokers in a military unit in Bangkok, Thailand. Setting: A military unit in Thailand. Subjects: One hundred and twenty-three male smokers from a military unit in Bangkok, who participated voluntarily in the study, were investigated. Sixty-six male non-smokers from the same unit were selected as controls. Fasting blood samples were collected for investigation of vitamin B12, folic acid and haematological variables. Results: The serum folic acid concentration of smokers was lower than that of non-smokers, but was not statistically significantly different. Haemoglobin was lower in smokers than in non-smokers; 16.3% of smokers were anaemic compared with only 3.0% of non-smokers. Anaemia was not related to folate deficiency. The white blood cell count was found to be higher in smokers than in non-smokers. Conclusion: The results of this study suggest that there were low serum folic acid concentrations in smokers compared with non-smokers, which might contribute to the development of vascular and cardiovascular diseases. The higher white blood cell count might be indicative alterations in the immune functions of smokers.|
|Appears in Collections:||Scopus 2001-2005|
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