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Title: Lack of association between toll-like receptor 2 polymorphisms and susceptibility to severe disease caused by Staphylococcus aureus
Authors: Catrin E. Moore
Shelley Segal
Anthony R. Berendt
Adrian V.S. Hill
Nicholas P.J. Day
John Radcliffe Hospital
Nuffield Orthopaedic Centre NHS Trust
Mahidol University
University of Oxford
Keywords: Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine
Issue Date: 1-Nov-2004
Citation: Clinical and Diagnostic Laboratory Immunology. Vol.11, No.6 (2004), 1194-1197
Abstract: To investigate a putative link between genetically determined variations in Toll-like receptor 2 (TLR2) and the occurrence of severe Staphylococcus aureus infection, the functional Arg753Gln single-nucleotide polymorphism and the GT repeat microsatellite in the TLR2 gene were examined in a large case-control study. No associations with disease or mortality attributable to these features were found.
ISSN: 1071412X
Appears in Collections:Scopus 2001-2005

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