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dc.contributor.authorManeekarn Chinworrungseeen_US
dc.contributor.authorPrasat Kittakoopen_US
dc.contributor.authorMasahiko Isakaen_US
dc.contributor.authorPacharee Maithipen_US
dc.contributor.authorSumalee Supothinaen_US
dc.contributor.authorYodhathai Thebtaranonthen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherThailand National Center for Genetic Engineering and Biotechnologyen_US
dc.date.accessioned2018-07-24T03:38:04Z-
dc.date.available2018-07-24T03:38:04Z-
dc.date.issued2004-04-01en_US
dc.identifier.citationJournal of Natural Products. Vol.67, No.4 (2004), 689-692en_US
dc.identifier.issn01633864en_US
dc.identifier.other2-s2.0-2042517594en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=2042517594&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/21208-
dc.description.abstractAn antimalarial macrocyclic polylactone, menisporopsin A (1), was isolated from a cell extract of the seed fungus Menisporopsis theobromae. The structure of 1 was elucidated on the basis of spectroscopic analysis and chemical transformations, with the absolute configuration established by application of the modified Mosher method and by using chiral HPLC. Menisporopsin A (1) possesses an unprecedented residue, 2,4-dihydroxy-6-(2,4-dihydroxy-n-pentyl)benzoic acid. This compound exhibited antimalarial activity, with an IC50 value of 4.0 μg mL -1, and antimycobacterial activity (MIC value of 50 μg mL -1).en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=2042517594&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleIsolation and Structure Elucidation of a Novel Antimalarial Macrocyclic Polylactone, Menisporopsin A, from the Fungus Menisporopsis theobromaeen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1021/np0304870en_US
Appears in Collections:Scopus 2001-2005

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