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|Title:||Infant schistosomiasis in Ghana: A survey in an irrigation community|
|Authors:||K. M. Bosompem|
Irene A. Bentum
W. K. Anyan
C. A. Brown
University of Ghana
Nagoya City University
|Keywords:||Immunology and Microbiology;Medicine|
|Citation:||Tropical Medicine and International Health. Vol.9, No.8 (2004), 917-922|
|Abstract:||We used a rapid, visually read, field applicable monoclonal antibody (MoAb)-dipstick assay for specific diagnosis of urinary schistosomiasis together with microscopy to determine the prevalence of infant schistosomiasis in a community in the Awutu-Efutu Senya District in the Central Region of Ghana. The study group consisted of 97 infants (51 males and 46 females) aged 2 months to 5 years. A total of 75 of 97 (77.3%) subjects submitted stool samples; none had Schistosoma mansoni. Three individuals (3.1%) had hookworms but there were no other intestinal helminths. The urinary schistosomiasis prevalence by MoAb-dipstick (30%) was higher (P < 0.05) than that estimated by microscopy (11.2%). However, three of nine (33.3%) microscopically confirmed cases tested MoAb-dipstick positive after pre-treatment of the urine specimen with heat. The youngest infant to be found infected with S. haematobium microscopically was 4 months old. Fifteen of 71 S. haematobium egg negative individuals tested dipstick positive, giving a dipstick specificity of 78.9% as compared with microscopy as gold standard test. The relative sensitivity of the dipstick was 100%.|
|Appears in Collections:||Scopus 2001-2005|
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