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|Title:||Chemotactic attraction of Necator hookworm filariform larvae to sodium chloride|
|Citation:||Southeast Asian Journal of Tropical Medicine and Public Health. Vol.35, No.SUPPL. 1 (2004), 112-115|
|Abstract:||An investigation was carried out to elucidate the chemotactic attractive behavior of Necator hookworm filariform larvae to inorganic substances in vitro. First, an optimal concentration of these larvae against sodium chloride solutions using the agarose plate assay method was determined. The sodium chloride concentration varied from 0.1 to 1.0 molar solutions. Distilled water ( DW ) was used as control in all experiments. 0.5 molar was found to be an appropriate concentration to examine larval attraction. Then, chloride compounds such as NaCl, KCl, CaCl2 and MgCl2 were tried at 0.5 molar concentration; many larvae were attracted to NaCl and some also to KCl. Therefore, the same experiment was conducted using 0.1 molar chemical concentrations. Many larvae were attracted to NaCl; however, some larvae again moved to KCl. Next, the concentration was changed to a higher range, 1.0 molar, and as a result, NaCl only attracted the larvae. The larvae were not attracted to 1.0 molar of KCl, CaCl2, and MgCl2. Since the chloride anion was found not to attract larvae of this species, another experiment was conducted with 0.5 molar of the sodium compounds, Na2CO3, NaOH, NaHCO3, NaCl, and DW. Na2CO3 had the strongest larval attracting ability. Other sodium compounds also attracted moderate numbers of larvae. In the inorganic substances tried, the sodium cation was found to attract Necator larvae, and thus the sodium cation might have an important role for finding and infecting hosts of Necator hookworm filariform larvae.|
|Appears in Collections:||Scopus 2001-2005|
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