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Title: Bioactive butenolides from Melodorum fruticosum
Authors: Patoomratana Tuchinda
Jinda Udchachon
Vichai Reutrakul
Thawatchai Santisuk
Walter C. Taylor
Norman R. Farnsworth
John M. Pezzuto
A. Douglas Kinghorn
Mahidol University
Thailand Royal Forest Department
The University of Sydney
University of Illinois at Chicago
Keywords: Agricultural and Biological Sciences;Biochemistry, Genetics and Molecular Biology
Issue Date: 1-Jan-1991
Citation: Phytochemistry. Vol.30, No.8 (1991), 2685-2689
Abstract: From leaves and branches of Melodorum fruticosum, five butenolides have been isolated: (4Z)-6-acetoxy-7-benzoyloxy-2,4-heptadien-4-olide, (4E)-6-acetoxy-7-benzoyloxy-2,4-heptadien-4-olide, (4Z)-7-benzoyloxy-6-hydroxy-2,4-heptadien-4-olide, (4E)-7-benzoyloxy-6-hydroxy-2,4-heptadien-4-olide and (4Z)-6-benzoyloxy-7-hydroxy-2,4-heptadien-4-olide. In addition, two known flavonoids (chrysin, pinocembrin) and benzoic acid were isolated. All butenolides showed cytotoxic activities in several tumour cell lines. The structures of the isolated compounds were elucidated by spectroscopic methods. © 1991.
ISSN: 00319422
Appears in Collections:Scopus 1991-2000

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