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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/22288
Title: Mutagenicity and antimutagenicity of hispidulin and hortensin, the flavonoids from Millingtonia hortensis L.
Authors: Malyn Chulasiri
Nuntawan Bunyapraphatsara
Primchanien Moongkarndi
Mahidol University
Keywords: Environmental Science;Medicine
Issue Date: 1-Jan-1992
Citation: Environmental and Molecular Mutagenesis. Vol.20, No.4 (1992), 307-312
Abstract: Studies of the mutagenicity and antimutagenicity of hispidulin and hortensin, the flavonoids from Millingtonia hortensis L. (Bignoniaceae), were performed using the liquid preincubation method of the Salmonella/microsome test. At the highest dose tested, 100 μg/plate, both compounds showed no mutagenicity and no cytotoxicity toward S. typhimurium strains TA98 and TA100 either in the presence or absence of S9 mix. However, these substances were antimutagens toward 2–aminoanthracene, aflatoxin Bl (in TA98), and dimethylnitrosamine (in TA100); but neither substance inhibited the direct mutagenic activity of 2‐(2‐furyl)‐3‐(5‐nitro‐2‐furyl) acrylamide nor that of sodium azide in strains TA98 and TA100, respectively. © 1992 Wiley‐Liss, Inc. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0026480572&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/22288
ISSN: 10982280
08936692
Appears in Collections:Scopus 1991-2000

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