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Title: การศึกษาความดันโลหิตในหนูแรทสายพันธุ์ความดันโลหิตสูงของศูนย์สัตว์ทดลองแห่งชาติ
Other Titles: Blood Pressure Study in Spontaneous Hypertensive Rat (SHR/KyoMlac), National Laboratory Animal Center
Authors: สุรชัย จันทร์ทิพย์
อภิสิทธิ เหล่าสันติสุข
พรรัตนา ช่อมณี
วสันต์ แก้วมณี
สุเมธ อาภาวงษ์
คิน หม่อง ซอ
กาญจนา เข่งคุ้ม
Surachai Chantip
Apisit laosantisuk
Pornrattana Chomanee
Wasan Keawmanee
Sumate Ampawong
Zaw, Khin Maung
Kanchana Kaengkhum
Mahidol University. Office of Academic Services, National Laboratory Animal Center
Mahidol University. Office of Veterinary Medical Care, National Laboratory Animal Center
Keywords: Spontaneous Hypertension Rat;Blood pressure
Issue Date: 2012
Abstract: Spontaneous hypertensive rat (SHR) is a genetic model of hypertension rat that is wildly accepted in biomedical research because its characteristic might be shared with idiopathic hypertension in human. National Laboratory Animal Center, Mahidol University has been breeding and selecting this strain (as subline namely SHR/KyoMlac) that kindly donated by Kyoto University, Japan. This study was conducted to evaluate the blood pressure (systolic and diastolic) and growth rate between SHR/KyoMlac (hypertensive) and WMN/NrsMlac (normotensive). The results showed that systolic blood pressure of adult hypertensive rat (130-150 mmHg) was significantly higher than adult normotensive rat (90-120 mmHg.) Contrast to growth rate of hypertensive rat was significantly lower than normotensive rat.
Description: Proceedings of 50th Kasetsart University Annual Conference; 2012 31 Jan-4 Feb; Bangkok
Appears in Collections:AC-Proceeding Document

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