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dc.contributor.authorChikara Ichinoen_US
dc.contributor.authorHiroaki Kiyoharaen_US
dc.contributor.authorNoppamas Soonthornchareonnonen_US
dc.contributor.authorWongsatit Chuakulen_US
dc.contributor.authorAki Ishiyamaen_US
dc.contributor.authorHitomi Sekiguchien_US
dc.contributor.authorMiyuki Namatameen_US
dc.contributor.authorKazuhiko Otoguroen_US
dc.contributor.authorSatoshi Omuraen_US
dc.contributor.authorHaruki Yamadaen_US
dc.contributor.otherKitasato Universityen_US
dc.contributor.otherThe Kitasato Instituteen_US
dc.contributor.otherMahidol Universityen_US
dc.identifier.citationPlanta Medica. Vol.72, No.7 (2006), 611-614en_US
dc.description.abstractDuring the screening of antimalarial substances, the 80% EtOH extract from the outer bark of Ochna integerrima Merr. (Ochnaceae) was shown to have a good anti-malarial activity (IC50 value: 6.5 μg/mL) whereas extracts from the inner barks of O. integerrima showed no antimalarial activity. Biflavanone (1), which had not been found previously from a natural plant source, was isolated as a potent antimalarial active ingredient (IC50 value: 80 ng/mL) from the extract of the outer barks. The stereoisomer of 1 (= compound 2) was also isolated from this plant; however, its activity was significantly lower than that of 1. © Georg Thieme Verlag KG Stuttgart.en_US
dc.rightsMahidol Universityen_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleAntimalarial activity of biflavonoids from Ochna integerrimaen_US
Appears in Collections:Scopus 2006-2010

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