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Title: Three distinct reactions of 3,4-dihydroisoquinolines with azlactones: Novel synthesis of imidazoloisoquinolin-3-ones, benzo[a]quinolizin-4-ones, and benzo[d]azocin-4-ones
Authors: Rattana Worayuthakarn
Nopporn Thasana
Somsak Ruchirawat
Chulabhorn Research Institute
Mahidol University
The Institute of Science and Technology for Research and Development, Mahidol University
Keywords: Biochemistry, Genetics and Molecular Biology;Chemistry
Issue Date: 7-Dec-2006
Citation: Organic Letters. Vol.8, No.25 (2006), 5845-5848
Abstract: (Diagram presented) A facile and direct synthetic entry to tricyclic imidazoloisoquinolin-3-ones and benzo[a]quinolizin-4-ones is reported based on the ring annulation of 1-unsubstituted and 1-substituted dihydroisoquinolines with azlactones under neutral conditions in a one-step procedure. Bicyclic 2,3-dihydrobenzo[djazocin-4-ones were also prepared using simple azlactone and 1-substituted dihydroisoquinolines in a one-pot reaction. © 2006 American Chemical Society.
ISSN: 15237060
Appears in Collections:Scopus 2006-2010

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