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Title: | Three distinct reactions of 3,4-dihydroisoquinolines with azlactones: Novel synthesis of imidazoloisoquinolin-3-ones, benzo[a]quinolizin-4-ones, and benzo[d]azocin-4-ones |
Authors: | Rattana Worayuthakarn Nopporn Thasana Somsak Ruchirawat Chulabhorn Research Institute Mahidol University The Institute of Science and Technology for Research and Development, Mahidol University |
Keywords: | Biochemistry, Genetics and Molecular Biology;Chemistry |
Issue Date: | 7-Dec-2006 |
Citation: | Organic Letters. Vol.8, No.25 (2006), 5845-5848 |
Abstract: | (Diagram presented) A facile and direct synthetic entry to tricyclic imidazoloisoquinolin-3-ones and benzo[a]quinolizin-4-ones is reported based on the ring annulation of 1-unsubstituted and 1-substituted dihydroisoquinolines with azlactones under neutral conditions in a one-step procedure. Bicyclic 2,3-dihydrobenzo[djazocin-4-ones were also prepared using simple azlactone and 1-substituted dihydroisoquinolines in a one-pot reaction. © 2006 American Chemical Society. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846272750&origin=inward http://repository.li.mahidol.ac.th/dspace/handle/123456789/22933 |
ISSN: | 15237060 |
Appears in Collections: | Scopus 2006-2010 |
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