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|Title:||Proteomic studies of galectin-3 expression in human thyroid diseases by immunodetection|
Chulabhorn Research Institute
Phramongkutklao College of Medicine
|Keywords:||Biochemistry, Genetics and Molecular Biology|
|Citation:||Cancer Genomics and Proteomics. Vol.3, No.6 (2006), 389-394|
|Abstract:||Galectin-3 expression in thyroid diseases was studied by 1-DE immunoblotting. Expression was markedly elevated in thyroid papillary carcinoma, compared to follicular adenoma, follicular carcinoma or non-neoplastic diseases. Galectin-3 expression was also elevated in malignant cancers of bone, breast, colon, esophagus, larynx, lung and ovary. Four cases of thyroid papillary carcinoma with metastasis gave 2-3 bands on 1-DE immunoblotting. 2-DE immunoblotting of gelectin-3 showed 3 dark spots with MW/pI 32.9/8.29, 31.0/8.40 and 30.0/8.40 and 2 light spots.|
|Appears in Collections:||Scopus 2006-2010|
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