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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/23294
Title: Causes of community-acquired bacteremia and patterns of antimicrobial resistance in Vientiane, Laos
Authors: Rattanaphone Phetsouvanh
Simmaly Phongmany
Douangdao Soukaloun
Bouachanh Rasachak
Vimone Soukhaseum
Seun Soukhaseum
Kamthavi Frichithavong
Sengmanivong Khounnorath
Bounthom Pengdee
Khamphong Phiasakha
Vang Chu
Khonesavanh Luangxay
Sayadeth Rattanavong
Konkam Sisouk
Valy Keolouangkot
Mayfong Mayxay
Andrew Ramsay
Stuart D. Blacksell
Jim Campbell
Bertrand Martinez-Aussel
Mayboun Heuanvongsy
Bounthapaany Bounxouei
Chanpheng Thammavong
Bounkong Syhavong
Michel Strobel
Sharon J. Peacock
Nicholas J. White
Paul N. Newton
Mahosot Hospital
Francophone Institute of Tropical Medicine
National University of Laos
University of Oxford
Mahidol University
UCL
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Nov-2006
Citation: American Journal of Tropical Medicine and Hygiene. Vol.75, No.5 (2006), 978-985
Abstract: There is no published information on the causes of bacteremia in the Lao PDR (Laos). Between 2000 and 2004, 4512 blood culture pairs were taken from patients admitted to Mahosot Hospital, Vientiane, Laos, with suspected community-acquired bacteremia; 483 (10.7%) cultures grew a clinically significant community-acquired organism, most commonly Salmonella enterica serovar typhi (50.9%), Staphylococcus aureus (19.0%), and Escherichia coli (12.4%). S. aureus bacteremia was common among infants (69.2%), while children 1-5 years had a high frequency of typhoid (44%). Multi-drug-resistant S. Typhi was rare (6%). On multiple logistic regression analysis, typhoid was associated with younger age, longer illness, diarrhea, higher admission temperature, and lower peripheral white blood cell count than non-typhoidal bacteremia. Empirical parenteral ampicillin and gentamicin would have some activity against ∼ 88% of clinically significant isolates at a cost of US $1.4/day, an important exception being B. pseudomallei. Bacteremic infants in this setting require an anti-staphylococcal antibiotic. Copyright © 2006 by The American Society of Tropical Medicine and Hygiene.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36549041261&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/23294
ISSN: 00029637
Appears in Collections:Scopus 2006-2010

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