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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/23354
Title: Emergence and clearance of gametocytes in uncomplicated Plasmodium falciparum malaria
Authors: Watcharapong Piyaphanee
Srivicha Krudsood
Noppadon Tangpukdee
Wipa Thanachartwet
Udomsak Silachamroon
Nantaporn Phophak
Chatnapra Duangdee
Orathai Haoharn
Suparat Faithong
Polrat Wilairatana
Wattana Leowattana
Sornchai Looareesuwan
Mahidol University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Mar-2006
Citation: American Journal of Tropical Medicine and Hygiene. Vol.74, No.3 (2006), 432-435
Abstract: We reviewed the records of 1,175 patients with uncomplicated Plasmodium falciparum malaria to determine the prevalence of gametocytemia. All patients were admitted and received artemisinin combination therapy. Blood films were checked daily until discharge. Circulating gametocytes were observed in 240 (20.2%) of patients and in most cases (222 of 240, 92.5%) gametocytemia was detected during the first 24 hours after admission. Gametocytes were first seen in 174 cases on admission, in 24 cases at 12 hours, and in 24 cases at 24 hours. The longest interval between admission and first appearance of gametocytes was 192 hours. The median gametocyte clearance time was 163 hours (range = 12-806) in the 219 patients in whom gametocytemia resolved. However, 21 patients (9.8%) still had gametocytemia on discharge. Gametocytemia generally is present within the first 24 hours after admission, and emerges in only 1.9% of patients later on during treatment with artemisinin. Copyright © 2006 by The American Society of Tropical Medicine and Hygiene.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33645975872&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/23354
ISSN: 00029637
Appears in Collections:Scopus 2006-2010

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