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Title: In vitro motility of a population of clinical Burkholderia Pseudomallei isolates
Authors: Khaemaporn Boonbumrung
Vanaporn Wuthiekanun
Sirirat Rengpipat
Nicholas P J Day
Sharon J. Peacock
Mahidol University
Chulalongkorn University
Nuffield Department of Clinical Medicine
Keywords: Medicine
Issue Date: 11-Oct-2006
Citation: Journal of the Medical Association of Thailand. Vol.89, No.9 (2006), 1506-1510
Abstract: Melioidosis, a serious infection caused by Burkholderia pseudomallei, is a leading cause of community-acquired sepsis in Northeast Thailand, and the commonest cause of death from community-acquired pneumonia in the Top End of Northern Australia. The causative organism is a Gram-negative, motile bacillus that is a facultative intracellular pathogen. B. pseudomallei flagella have been proposed as a possible vaccine candidate and putative virulence determinant. Flagella expression was highly conserved for 205 clinical B. pseudomallei isolates, as defined by in vitro swim and swarm motility assays. No association was found between motility and clinical factors including bacteremia and death.
ISSN: 01252208
Appears in Collections:Scopus 2006-2010

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