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Title: Distribution of hsp65 PCR-restriction enzyme analysis patterns among Mycobacterium avium complex isolates in Thailand
Authors: Therdsak Prammananan
Saranya Phunpruch
Nipa Tingtoy
Somboon Srimuang
Angkana Chaiprasert
Thailand National Center for Genetic Engineering and Biotechnology
King Mongkut's Institute of Technology Ladkrabang
Mahidol University
Keywords: Medicine
Issue Date: 1-Oct-2006
Citation: Journal of Clinical Microbiology. Vol.44, No.10 (2006), 3819-3821
Abstract: A total of 227 clinical Mycobacterium avium complex isolates from Thailand were differentiated into species and types by using PCR-restriction enzyme analysis of hsp65. The distribution of types showed the predominance of M. avium I (77%) in blood specimens, whereas M. intracellulare I was more commonly found in pulmonary specimens (44.2%). In addition, infections with M. avium were more likely to be found in younger adults (20 to 39 years old), while infections with M. intracellulare were more likely to be found in older adults (≥60 years old). Our results provide the useful epidemiological information that some particular types have more invasive and virulent characters than others. Copyright © 2006, American Society for Microbiology. All Rights Reserved.
ISSN: 00951137
Appears in Collections:Scopus 2006-2010

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