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http://repository.li.mahidol.ac.th/dspace/handle/123456789/23702| Title: | Plasmepsin II inhibitory activity of alkoxylated and hydroxylated chalcones |
| Authors: | Nongluk Sriwilaijaroen Mei Liu Mei Lin Go Prapon Wilairat Mahidol University University of |
| Keywords: | Medicine |
| Issue Date: | 1-Jul-2006 |
| Citation: | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.4 (2006), 607-612 |
| Abstract: | Sixteen antimalarial alkoxylated and hydroxylated chalcones were tested for their ability to inhibit recombinant plasmepsin II in vitro. The best inhibitory compounds had either a chloro or dimethylamino group at the 4-position of phenyl ring A in the chalcone template. Combination of the chalcones with chloroquine showed additivity or mild antagonism of Plasmodium falciparum K1 growth in culture. |
| URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750217087&origin=inward http://repository.li.mahidol.ac.th/dspace/handle/123456789/23702 |
| ISSN: | 01251562 |
| Appears in Collections: | Scopus 2006-2010 |
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