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dc.contributor.authorPiriyaporn Chongtrakoolen_US
dc.contributor.authorTeruyo Itoen_US
dc.contributor.authorXiao Xue Maen_US
dc.contributor.authorYoko Kondoen_US
dc.contributor.authorSuwanna Trakulsomboonen_US
dc.contributor.authorChuntima Tiensasitornen_US
dc.contributor.authorMantana Jamklangen_US
dc.contributor.authorTavinun Chavaliten_US
dc.contributor.authorJae Hoon Songen_US
dc.contributor.authorKeiichi Hiramatsuen_US
dc.contributor.otherJuntendo Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherSungkyunkwan Universityen_US
dc.date.accessioned2018-08-20T07:19:36Z-
dc.date.available2018-08-20T07:19:36Z-
dc.date.issued2006-03-01en_US
dc.identifier.citationAntimicrobial Agents and Chemotherapy. Vol.50, No.3 (2006), 1001-1012en_US
dc.identifier.issn00664804en_US
dc.identifier.other2-s2.0-33644637478en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644637478&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/23818-
dc.description.abstractA description of staphylococcal cassette chromosome mec (SCCmec) elements carried by 615 methicillin-resistant Staphylococcus aureus (MRSA) strains isolated in 11 Asian countries is reported, and a novel nomenclatural system based on their structures is proposed. The 615 strains were classified as type 3A (370 strains), type 2A (207 strains), type 2B (32 strains), type 1B (1 strain), and nontypeable (5 strains). The previously reported type III SCCmec (DDBJ/EMBL/GenBank accession no. AB037671) carried by the MRSA strain 85/2082 was ascertained to be composed of two SCC elements, type 3A SCCmec and SCCmercury. PCR analysis indicated that 310 of 370 type 3A SCCmec strains carried both SCC elements. These strains were prevalent in eight countries: Thailand, Sri Lanka, Indonesia, Vietnam, Philippines, Saudi Arabia, India, and Singapore. The remaining 60 type 3A SCCmec strains differed with respect to the left extremity polymorphism or to the presence of ccrC. Among these, two were identified as carrying only type 3A SCCmec elements, but their left extremities differed. Type 2A SCCmec strains predominated in Korea and Japan, although the frequency of the presence of ant(4′)-1 gene downstream of mecA varied (53% for Korean strains; 93% for Japanese strains). Various SCCmec elements were identified in the tested strains, and limited numbers were identified by their multilocus sequence typing genotypes. These data suggest that numerous MRSA clones are disseminated in Asian hospitals, and these consist of minor clones that are presumed to have arisen locally and major clones that are presumed to have been introduced from other countries. Copyright © 2006, American Society for Microbiology. All Rights Reserved.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33644637478&origin=inwarden_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleStaphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: A proposal for a new nomenclature for SCCmec elementsen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1128/AAC.50.3.1001-1012.2006en_US
Appears in Collections:Scopus 2006-2010

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