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Title: Rickettsial infections and fever, Vientiane, Laos
Authors: Simaly Phongmany
Jean Marc Rolain
Rattanaphone Phetsouvanh
Stuart D. Blacksell
Vimone Soukkhaseum
Bouachanh Rasachack
Khamphong Phiasakha
Surn Soukkhaseum
Khamthavi Frichithavong
Vang Chu
Valy Keolouangkhot
Bertrand Martinez-Aussel
Ko Chang
Chirapha Darasavath
Oudayvone Rattanavong
Siho Sisouphone
Mayfong Mayxay
Sisouphane Vidamaly
Philippe Parola
Chanpheng Thammavong
Mayboun Heuangvongsy
Bounkong Syhavong
Didier Raoult
Nicholas J. White
Paul N. Newton
Mahosot Hospital
Universite de la Mediterranee Aix-Marseille II
University of Oxford
Mahidol University
National University of Laos
Francophone Institute of Tropical Medicine
Keywords: Medicine
Issue Date: 1-Jan-2006
Citation: Emerging Infectious Diseases. Vol.12, No.2 (2006), 256-262
Abstract: Rickettsial diseases have not been described previously from Laos, but in a prospective study, acute rickettsial infection was identified as the cause of fever in 115 (27%) of 427 adults with negative blood cultures admitted to Mahosot Hospital in Vientiane, Laos. The organisms identified by serologic analysis were Orientia tsutsugamushi (14.8%), Rickettsia typhi (9.6%), and spotted fever group rickettsia (2.6% [8 R. helvetica, 1 R. felis, 1 R. conorii subsp. indica, and 1 Rickettsia "AT1"]). Patients with murine typhus had a lower frequency of peripheral lymphadenopathy than those with scrub typhus (3% vs. 46%, p<0.001). Rickettsioses are an underrecognized cause of undifferentiated febrile illnesses among adults in Laos. This finding has implications for the local empiric treatment of fever.
ISSN: 10806059
Appears in Collections:Scopus 2006-2010

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