Please use this identifier to cite or link to this item:
|Title:||Cytotoxic mycoepoxydiene derivatives from an endophytic fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus|
Chulabhorn Research Institute
The Institute of Science and Technology for Research and Development, Mahidol University
|Keywords:||Agricultural and Biological Sciences;Chemistry;Pharmacology, Toxicology and Pharmaceutics|
|Citation:||Planta Medica. Vol.73, No.13 (2007), 1418-1420|
|Abstract:||Mycoepoxydiene (1) and derivatives, deacetylmycoepoxydiene (2) and 2,3-dihydromycoepoxydiene (3), were isolated from a broth extract of the endophytic fungus, Phomopsis sp., which was isolated from a Thai medicinal plant, Hydnocarpus anthelminthicus. Compounds 1 and 2 exhibited potent cytotoxic activity, while a dihydro derivative 3 was inactive. The present work suggests that the α,β-unsaturated lactone moiety in mycoepoxydienes might be responsible for the cytotoxicity. © Georg Thieme Verlag KG Stuttgart.|
|Appears in Collections:||Scopus 2006-2010|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.