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|Title:||Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis|
Allen C. Cheng
Nicholas P.J. Day
Sharon J. Peacock
Menzies School of Health Research
Nuffield Department of Clinical Medicine
|Keywords:||Biochemistry, Genetics and Molecular Biology;Immunology and Microbiology;Medicine|
|Citation:||Clinical and Vaccine Immunology. Vol.14, No.1 (2007), 110-113|
|Abstract:||Five enzyme-linked immunosorbent assays developed to detect antibodies to different Burkholderia pseudomallei antigen preparations were evaluated as diagnostic tests for melioidosis in northeast Thailand. The highest diagnostic indices were observed for an affinity-purified antigen (sensitivity, 82%; specificity, 72%) and crude B. pseudomallei antigen (sensitivity, 81%; specificity, 70%), an improvement over the indirect hemagglutination assay (sensitivity, 73%; specificity, 64%). Copyright © 2007, American Society for Microbiology. All Rights Reserved.|
|Appears in Collections:||Scopus 2006-2010|
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