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|Title:||Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis|
Thailand National Center for Genetic Engineering and Biotechnology
The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association
|Keywords:||Immunology and Microbiology;Medicine|
|Citation:||Tuberculosis. Vol.87, No.6 (2007), 498-501|
|Abstract:||The patterns of variable-number tandem repeats (VNTR) genotypes of a clonal group of Mycobacterium tuberculosis Beijing isolates with very similar IS6110-restriction fragment length polymorphism (RFLP) patterns were studied. Differences between VNTR were mostly by a single repeat unit. However, a multiple-unit change also occurred. This suggests that a mechanism other than the slipped-strand mispairing might be responsible for the instability of VNTR in M. tuberculosis as well. This finding is useful for inferring phylogenetics of M. tuberculosis based on the VNTR genotypes. © 2007 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Scopus 2006-2010|
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