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Title: | Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis |
Authors: | Pamaree Billamas Nat Smittipat Tada Juthayothin Arunee Thong-On Norio Yamada Hideki Yanai Prasit Palittapongarnpim Thailand National Center for Genetic Engineering and Biotechnology Mahidol University The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association |
Keywords: | Immunology and Microbiology;Medicine |
Issue Date: | 1-Nov-2007 |
Citation: | Tuberculosis. Vol.87, No.6 (2007), 498-501 |
Abstract: | The patterns of variable-number tandem repeats (VNTR) genotypes of a clonal group of Mycobacterium tuberculosis Beijing isolates with very similar IS6110-restriction fragment length polymorphism (RFLP) patterns were studied. Differences between VNTR were mostly by a single repeat unit. However, a multiple-unit change also occurred. This suggests that a mechanism other than the slipped-strand mispairing might be responsible for the instability of VNTR in M. tuberculosis as well. This finding is useful for inferring phylogenetics of M. tuberculosis based on the VNTR genotypes. © 2007 Elsevier Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=35348841489&origin=inward http://repository.li.mahidol.ac.th/dspace/handle/123456789/24501 |
ISSN: | 14729792 |
Appears in Collections: | Scopus 2006-2010 |
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