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Title: Evolution of some variable-number tandem repeat loci among a group of Beijing strains of Mycobacterium tuberculosis
Authors: Pamaree Billamas
Nat Smittipat
Tada Juthayothin
Arunee Thong-On
Norio Yamada
Hideki Yanai
Prasit Palittapongarnpim
Thailand National Center for Genetic Engineering and Biotechnology
Mahidol University
The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Nov-2007
Citation: Tuberculosis. Vol.87, No.6 (2007), 498-501
Abstract: The patterns of variable-number tandem repeats (VNTR) genotypes of a clonal group of Mycobacterium tuberculosis Beijing isolates with very similar IS6110-restriction fragment length polymorphism (RFLP) patterns were studied. Differences between VNTR were mostly by a single repeat unit. However, a multiple-unit change also occurred. This suggests that a mechanism other than the slipped-strand mispairing might be responsible for the instability of VNTR in M. tuberculosis as well. This finding is useful for inferring phylogenetics of M. tuberculosis based on the VNTR genotypes. © 2007 Elsevier Ltd. All rights reserved.
ISSN: 14729792
Appears in Collections:Scopus 2006-2010

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