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Title: Cardiac dimensions and function in children with obesity
Authors: Anant Khositseth
Umaporn Suthutvoravut
Nalinee Chongviriyaphan
Suwanna Ruangkanchanasetr
Mahidol University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Keywords: Medicine
Issue Date: 1-Dec-2007
Citation: Indian Heart Journal. Vol.59, No.2 (2007), 142-146
Abstract: BACKGROUND: Obesity can cause alterations in cardiac dimensions and function. Cardiac dysfunction during childhood may affect the quality of life in adulthood. This study evaluated left ventricular (LV) dimensions, systolic function and left ventricular myocardial performance index (LMPI) in children with obesity. METHODS AND RESULTS: Thirty-three obese children with mean age of 9.8 ± 2.4 years, weight 61.3 ± 20.8 kg, BMI 29.5 ± 5.8 kg/m2 and percentage of actual weight to ideal body weight for height (%IBW) 170 ± 25%, underwent echocardiography to assess LV dimensions, systolic and global functions. There were 2, 14 and 17 children with mild (≤140%IBW), moderate (141-160% IBW) and severe obesity (>160%IBW), respectively. The mean ratio of left ventricular end-diastolic dimension (LVEDD) to predicted LVEDD expressed in percentage (%LVEDD) was 98.3 ± 7.8%, the left ventricular shortening fraction (LVFS) was 37.5 ± 4.9% and the left ventricular ejection fraction (LVEF) was 67.5 ± 5.9%. All were within normal range except that 2 children (6%) had mild LV dilatation. The mean LMPI was 0.35 ± 0.08. However, 11 children (33%) had abnormal LMPI (>0.4). The severity of obese children did not correlate with the global LV dysfunction. CONCLUSION: The left ventricular dimensions and systolic function in children with obesity were essentially normal. LMPI which indicates LV global function was found to be abnormal in 33% of children with obesity and may be used to do early detection of LV global dysfunction.
ISSN: 00194832
Appears in Collections:Scopus 2006-2010

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