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Title: Primary hepatic clear cell myomelanocytic tumor: Case report and review of the literature
Authors: Noppadol Larbcharoensub
Patcharee Karnsombut
Janjira Jatchavala
Yodying Wasutit
Prawat Nitiyanant
Mahidol University
Keywords: Medicine
Issue Date: 1-Dec-2007
Citation: APMIS. Vol.115, No.12 (2007), 1454-1459
Abstract: A case of hepatic clear cell myomelanocytic tumor in a 31-year-old woman presenting clinically with abdominal pain is reported. Histopathologic examination showed a lesion characterized by a population of large epithelioid cells with clear or eosinophilic granular cytoplasm, rich in glycogen. Immunohistochemically, the tumor cells were positive for HMB-45, Melan-A and muscle-specific actin, but negative for epithelial markers, desmin, S-100 protein, and neuroendocrine markers. Ultrastructurally, the tumor cells had abundant glycogen, well-developed rough endoplasmic reticulum, microtubules and aberrant melanosomes. Clinical and pathologic features with a brief review of the relevant literature for hepatic CCMMT as a variant of perivascular epithelioid cell tumor (PEComa) are discussed. Copyright © Apmis 2007.
ISSN: 16000463
Appears in Collections:Scopus 2006-2010

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