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Title: Detection of VacA gene specific for Helicobactor pylori in hepatocellular carcinoma and cholangiocarcinoma specimens of Thai patients
Authors: Kawin Leelawat
Nithikoon Suksumek
Surang Leelawat
Usa Lek-Uthai
Rajavithi Hospital
Vajira Hospital
Rangsit University
Mahidol University
Keywords: Medicine
Issue Date: 1-Sep-2007
Citation: Southeast Asian Journal of Tropical Medicine and Public Health. Vol.38, No.5 (2007), 881-885
Abstract: In order to investigate and compare the presence of Helicobacter pylori VacA in primary liver cancer specimens (12 hepatocellular carcinoma and 6 cholangiocarcinoma) and control liver specimens (7 non-primary liver cancer) from Thai patients who underwent liver resection, H. pylori VacA gene was assayed in extracted DNA by real-time polymerase chain reaction. The selected amplicons revealed high homology compared with H. pylori VacA sequence. H. pylori VacA gene was detected in all primary liver cancer specimens and in 71% (5/7) of control liver specimens.
ISSN: 01251562
Appears in Collections:Scopus 2006-2010

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