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Title: Leptospirosis in Takeo province, Kingdom of Cambodia, 2003
Authors: Heng Seng
Touch Sok
Waraluk Tangkanakul
Wimol Petkanchanapong
Uraiwan Kositanont
Hem Sareth
Bunleng Hor
Chuleeporn Jiraphongsa
Bureau of Epidemiology
Ministry of Health Cambodia
Thailand Ministry of Public Health
Mahidol University
Takeo Provincial Hospital
National HIV/AIDS
Keywords: Medicine
Issue Date: 1-Mar-2007
Citation: Journal of the Medical Association of Thailand. Vol.90, No.3 (2007), 546-551
Abstract: Background: In Cambodia, epidemiology and disease burden of leptospirosis were not addressed as they do not have an existing surveillance system and have limitations on their laboratory diagnosis. Objective: Define the existence of leptospirosis and determine the antibodies to serovars of leptospires in Cambodia. Material and Method: One hundred and twenty-one suspected cases of leptospirosis were enrolled in this cross-sectional study, between September 8 and November 30, 2003 from Takeo Provincial Hospital in Doun Keo District, Cambodia. Results: Common clinical manifestations were fever (96%), headache (92%), and myalgia (87%). Common risk behaviors were throwing garbage on the ground (84%), pulling out sprouts (77%), fertilizing (49%), and plowing (47%). Microscopic agglutination test result confirmed four cases and polymerase chain reaction test result confirmed seven cases. Two cases each showed antibodies to serovars Javanica and Australis. An estimated annual incidence of leptospirosis in Takeo province was 7.65 per 100,000 populations. Further studies to define epidemiology and burden of disease are needed. Conclusion: Increasing awareness and knowledge on leptospirosis among people are necessary to decrease the impact of leptospirosis in Cambodia.
ISSN: 01252208
Appears in Collections:Scopus 2006-2010

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