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Title: The development and validation of a diabetes risk score for high-risk Thai adults
Authors: Prasit Keesukphan
Suwannee Chanprasertyothin
Boonsong Ongphiphadhanakul
Gobchai Puavilai
Mahidol University
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Keywords: Medicine
Issue Date: 1-Jan-2007
Citation: Journal of the Medical Association of Thailand. Vol.90, No.1 (2007), 149-154
Abstract: Objective: To develop a simple risk score to identify high-risk individuals for diabetes screening in Thailand. Material and Method: The authors analyzed data from 75-g oral glucose tolerance tests performed in 159 males and 270 females, aged 48.4 ± 10.9 years. Results: The independent variables associated with diabetes included age (p < 0.001), BMI (p < 0.01) and known history of hypertension (HHT) (p < 0.01). The risk equation was Y = 3age + 5BMI +50HHT. At the cut-off Y value of 240, the sensitivity and specificity for having diabetes were 96.8% and 24.0%, respectively. The positive predictive value was 17.8% and the negative predictive value was 97.8%. Using the equation in a validation group comprising 1617 subjects, it was found that 560 (34.6%) diabetes screenings could be saved while 28 subjects (12.8%) with diabetes would be missed. Conclusion: The authors have developed a simple risk scoring method that should be helpful in decreasing the number of unnecessary screening and optimizing the costs associated with diabetes screening.
ISSN: 01252208
Appears in Collections:Scopus 2006-2010

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