Please use this identifier to cite or link to this item:
|Title:||Seroprevalence of human herpesvirus-8 (HHV-8) in countries of Southeast Asia compared to the USA, the Caribbean and Africa|
A. W. Norhanom
A. K. Chandana
S. A.R. Kulpradist
P. H. Levine
Advanced Biotechnologies Inc.
University of Malaya
University of Southern California
University of Maryland, Baltimore
National Cancer Institute
George Washington University School of Medicine and Health Sciences
Orchestra Therapeutics Inc
Med. Res. Found. of Trinidad and T.
Chester Beatty Research Institute
|Keywords:||Biochemistry, Genetics and Molecular Biology;Medicine|
|Citation:||British Journal of Cancer. Vol.81, No.5 (1999), 893-897|
|Abstract:||Seroprevalence of HHV-8 has been studied in Malaysia, India, Sri Lanka, Thailand, Trinidad, Jamaica and the USA, in both healthy individuals and those infected with HIV. Seroprevalence was found to be low in these countries in both the healthy and the HIV-infected populations. This correlates with the fact that hardly any AIDS-related Kaposi's sarcoma has been reported in these countries. In contrast, the African countries of Ghana, Uganda and Zambia showed high seroprevalences in both healthy and HIV-infected populations. This suggests that human herpes virus-8 (HHV-8) may be either a recently introduced virus or one that has extremely low infectivity. Nasopharyngeal and oral carcinoma patients from Malaysia, Hong Kong and Sri Lanka who have very high EBV titres show that only 3/82 (3.7%) have antibody to HHV-8, demonstrating that there is little, if any, cross-reactivity between antibodies to these two gamma viruses.|
|Appears in Collections:||Scopus 1991-2000|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.