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dc.contributor.authorVasant Sumethkulen_US
dc.contributor.authorSiribha Changsirikulchaien_US
dc.contributor.authorPiyanuch Radinahameden_US
dc.contributor.authorPanas Chalermsanyakornen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-09-07T08:50:34Z-
dc.date.available2018-09-07T08:50:34Z-
dc.date.issued1999-12-01en_US
dc.identifier.citationAsian Pacific Journal of Allergy and Immunology. Vol.17, No.4 (1999), 281-287en_US
dc.identifier.issn0125877Xen_US
dc.identifier.other2-s2.0-0032740475en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0032740475&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/25417-
dc.description.abstractThe impact of vasculitis as a cause of primary rapidly progressive crescentic glomerulonephritis (RPGN) was examined in patients with Thai ethnic by antineutrophil cytoplasmic antibody (ANCA) test. Thirty patients found in a six years study period were included. Patients' mean age was 34.8 ± 16.4 years. Mean crescent score was 86.2 ± 22.9%. ANCA proved positive in fifteen patients. This helps to differentiate vasculitis associated (ANCA positive) from nonvasculitis (ANCA negative) RPGN. Incidence of immune complex type RPGN (46.6%) is higher than the Caucasians while the incidence of antiglomerular basement membrane antibody (anti-GBM disease) is much lower. More vasculitis patients were treated with cyclophosphamide (n = 11) than the nonvasculitis group (n = 2). Mean renal survival time of ANCA and non-ANCA associated patients were 26.69 and 14.16 months, respectively. Renal survival of all patients is significantly worse if associated with a high entry creatinine (> 6 mg/dl). Our results show that vasculitis associated RPGN is not an uncommon disease in the Thai population and can be recognized initially by ANCA test.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0032740475&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleAntineutrophil cytoplasmic antibody (ANCA) and rapidly progressive crescentic glomerulonephritis in Thai populationen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
Appears in Collections:Scopus 1991-2000

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