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Title: Clinical presentation of hospitalized adult patients with HIV infection and AIDS in Bangkok, Thailand
Authors: Somsit Tansuphasawadikul
Pauli N. Amornkul
Chana Tanchanpong
Khanchit Limpakarnjanarat
Jaranit Kaewkungwal
Sirirat Likanonsakul
Boonchuey Eampokalap
Thananda Naiwatanakul
Dwip Kitayaporn
Nancy L. Young
Dale J. Hu
Timothy D. Mastro
Bamrasnaradura Infectious Disease Institute
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
HIV/AIDS Collaboration
Mahidol University
Bureau of Epidemiology
Thailand Ministry of Public Health
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Aug-1999
Citation: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. Vol.21, No.4 (1999), 326-332
Abstract: Objective: To characterize the clinical spectrum of disease and immune status of adult HIV-1-infected patients in Bangkok. Design: Cross-sectional survey of hospital admissions. Methods: From November 1993 through June 1996, demographic, clinical, and laboratory data were collected from HIV-infected inpatients (≥14 years old) at an infectious diseases hospital. Results: Of 16,717 persons admitted, 3112 (18.6%) were HIV-seropositive, 2261 of whom were admitted for the first time. Of 2261, 1926 (85.2%) were male, 1942 (85.9%) had been infected heterosexually or by means not related to drug use, 319 (14.1%) were injection drug users (IDUs), and 1553 (68.7%) had AIDS. The most common AIDS-defining conditions were extrapulmonary cryptococcosis (EPC; 38.4%), tuberculosis (TB; 37.4%), and wasting syndrome (WS; 8.1%). IDUs were more likely (p < .05) to have TB or WS but less likely (p < .05) to have EPC or Pneumocystis carinii pneumonia than patients with no history of injection drug use. Lymphocyte counts were measured for 2047 (90.5%) patients; 81.8% had ≤1500 lymphocytes/μl. Conclusion: These HIV-infected patients were admitted with severe immunosuppression. Cryptococcosis and TB are major problems and differ in prevalence among IDUs and persons infected sexually. Clinical and immunologic information is critical in improving the lives of HIV-infected persons in Asia through prevention, treatment, and prophylaxis.
ISSN: 10779450
Appears in Collections:Scopus 1991-2000

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