Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/25473
Full metadata record
DC FieldValueLanguage
dc.contributor.authorR. E.L. Paulen_US
dc.contributor.authorA. Brockmanen_US
dc.contributor.authorR. N. Priceen_US
dc.contributor.authorC. Luxemburgeren_US
dc.contributor.authorN. J. Whiteen_US
dc.contributor.authorS. Looareesuwanen_US
dc.contributor.authorF. Nostenen_US
dc.contributor.authorK. P. Dayen_US
dc.contributor.otherUniversity of Oxforden_US
dc.contributor.otherShoklo Malaria Research Uniten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherJohn Radcliffe Hospitalen_US
dc.contributor.otherInstitut Pasteur, Parisen_US
dc.date.accessioned2018-09-07T08:52:01Z-
dc.date.available2018-09-07T08:52:01Z-
dc.date.issued1999-01-01en_US
dc.identifier.citationTransactions of the Royal Society of Tropical Medicine and Hygiene. Vol.93, No.6 (1999), 587-593en_US
dc.identifier.issn00359203en_US
dc.identifier.other2-s2.0-0033397070en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0033397070&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/25473-
dc.description.abstractGenetic characterization of Plasmodium falciparum infections in north-western Thailand, a region of low transmission intensity (1 infection/person each year), has found a comparable number of parasite genotypes per infected person to regions with hyperendemic malaria. Clone multiplicity and parasite diversity were found to be homogeneous across 129 infected individuals comprising a range of age-groups (1.32 parasite genotypes; n = 98), patients (aged 2-16 years) with recrudescent infections (1.54; n = 13), and pregnant women (1.61; n = 18). Individuals belonging to groups with a high risk of infection, as deduced by clinical epidemiology, did not harbour a higher number of clones per infection, nor greater parasite diversity than low-risk groups. In fact, multiple genotype infections were as common in low-risk groups, suggesting that there is frequent transmission of polyclonal infections from a single inoculum, rather than superinfection. Such a polyclonal transmission system would enable generation of extensive parasite diversity by recombination, despite the low level of transmission. However, co-infection with P. vivax was associated with fewer P. falciparum genotypes per infection.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0033397070&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleGenetic analysis of Plasmodium falciparum infections on the north-western border of Thailanden_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1016/S0035-9203(99)90057-3en_US
Appears in Collections:Scopus 1991-2000

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.