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Title: A review of the spectrum of clinical ocular fundus findings in P. falciparum malaria in African children with a proposed classification and grading system
Authors: Susan Lewallen
Simon P. Harding
Jeff Ajewole
W. Edmund Schulenburg
Malcolm E. Molyneux
Kevin Marsh
Stanley Usen
Nicholas J. White
Terrie E. Taylor
The University of British Columbia
Royal Liverpool and Broadgreen University Hospitals NHS Trust
National Eye Care Project
Western Eye Hospital
University of Malawi College of Medicine
University of Liverpool
Kenya Medical Research Institute
Medical Research Council Laboratories Gambia
Mahidol University
Michigan State University
Keywords: Immunology and Microbiology;Medicine
Issue Date: 1-Jan-1999
Citation: Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.93, No.6 (1999), 619-622
Abstract: Ocular fundus pathology in Plasmodium falciparum malaria is common and has prognostic significance. We have made a collaborative effort to document the ocular features in several populations. Based on examination of 735 patients in Malawi, Kenya and The Gambia by direct and indirect ophthalmoscopy with dilated pupils, we have determined that the 5 distinct clinical features (in order of frequency) include retinal whitening, haemorrhages, unique vessel abnormalities, papilloedema, and cotton wool spots. Photographs and descriptions of these are presented, along with a proposed grading scheme.
ISSN: 00359203
Appears in Collections:Scopus 1991-2000

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