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dc.contributor.authorPornpimon Phuapraditen_US
dc.contributor.authorWandee Varavithyaen_US
dc.contributor.authorKanda Vathanophasen_US
dc.contributor.authorRawiwan Sangchaien_US
dc.contributor.authorAmornrath Podhipaken_US
dc.contributor.authorUmaporn Suthutvoravuten_US
dc.contributor.authorSupachara Nopchindaen_US
dc.contributor.authorVinitta Chantraruksaen_US
dc.contributor.authorFerdinand Haschkeen_US
dc.contributor.otherFaculty of Medicine, Ramathibodi Hospital, Mahidol Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherNestle S.A.en_US
dc.identifier.citationJournal of the Medical Association of Thailand. Vol.82, No.SUPPL. (1999)en_US
dc.description.abstractThis study was conducted at Pakkred Babies Home, Bangkok, Thailand; with the hypothesis that children receiving probiotic-supplemented milk-based formula may be protected from developing diarrheal diseases. Salivary rotavirus-specific IgA antibody was used as an indicator of rotavirus infection. One hundred and seventy-five children, aged 6-36 months, were enrolled in the study. They were divided into 3 groups according to the type of formula given. There were 81 episodes of diarrhea during an 8-month study period, most of which were caused by bacterial enteropathogens. Ninety-seven pairs of salivary samples were adequate for the analysis of rotavirus antibody. Among 23 children receiving milk-based follow-up formula and serving as control group, 30.4 per cent of them had ≥ 4-fold increase in the antibody titre, indicating subclinical rotavirus infection. The majority of children in the other 2 study groups, receiving the same formula supplemented with either Bifidobacterium Bbl2 alone or together with Streptococcus thermophilus, had no significant change in the antibody titres between the two time points. The results of this study support our hypothesis that children receiving bifidobacteria-supplemented milk-based formula may be protected against symptomatic rotavirus infection.en_US
dc.rightsMahidol Universityen_US
dc.titleReduction of rotavirus infection in children receiving bifidobacteria-supplemented formulaen_US
Appears in Collections:Scopus 1991-2000

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