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Title: Treatment of psoriasis vulgaris with topical vitamin D analogue (calcipotriol): Open multicenter study
Authors: Preya Kullavanijaya
Pimonpun Gritiyarangsan
Porntip Huiprasert
Vichit Leenutaphong
Thailand Ministry of Public Health
Chulalongkorn University
Mahidol University
Keywords: Medicine
Issue Date: 1-Oct-1999
Citation: Journal of the Medical Association of Thailand. Vol.82, No.10 (1999), 973-976
Abstract: Sixty one psoriasis patients, 46 males and 15 females (mean age: 40 years, range: 20-70 years) with baseline PASI score of 7.16 (± 3.66 SD) were enrolled in the study. All subjects were advised to apply calcipotriol ointment twice daily for 6 weeks. Six patients dropped out, five after 2 weeks and one after 4 weeks of treatment. PASI scores of fifty five patients were reduced to 2.16 per cent, 46.78 per cent and 55.55 per cent by 2 weeks, 4 weeks and 6 weeks respectively versus the baseline. Overall clinical assessment showed remission in 7.27 per cent marked improvement 74.54 per cent and slight improvement 18.18 per cent. Mild erythema were observed in fourteen patients (22.95%) that were mostly transient except for one patient. Serum creatinine, calcium and phosphate were normal throughout the study.
ISSN: 01252208
Appears in Collections:Scopus 1991-2000

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