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dc.contributor.authorKanokvalai Kulthananen_US
dc.contributor.authorRutsanee Akaraphanthen_US
dc.contributor.authorThada Piamphongsanten_US
dc.contributor.authorPreya Kullavanijayaen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherThailand Ministry of Public Healthen_US
dc.identifier.citationJournal of the Medical Association of Thailand. Vol.82, No.7 (1999), 706-712en_US
dc.description.abstractBackground: Linear IgA bullous dermatosis (LAD) of childhood is a rare acquired subepidermal blistering disease of young children. Most of the studies were reported from the USA and European countries. Method: Twelve cases of Thai patients diagnosed as LAD of childhood were analyzed concerning clinical, histopathological, immunopathological findings including treatment responses and courses compared with those of Caucasians. Result: The mean age of onset was 5.1 years. The areas of common involvement were the perioral region, lower abdomen, perineum, buttock, inner thighs and extremities. Histopathology in half of the cases showed features of dermatitis herpetiformis or bullous pemphigoid. All patients had positive linear IgA band at the basement membrane zone (BMZ) by direct immunofluorescence. Only one patient had positive circulating anti BMZ antibody at the titer of 1:10. Most patients res-ponded well to dapsone. The mean duration before remission was 1.9 years. Conclusion: Our study in Thai patients with LAD of childhood produced data similar to previous studies carried out in the Caucasian nations.en_US
dc.rightsMahidol Universityen_US
dc.titleLinear IgA bullous dermatosis of childhood: A long term studyen_US
Appears in Collections:Scopus 1991-2000

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