Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/25900
Full metadata record
DC FieldValueLanguage
dc.contributor.authorE. E. Nakayamaen_US
dc.contributor.authorC. Wasien_US
dc.contributor.authorA. Ajisawaen_US
dc.contributor.authorA. Iwamotoen_US
dc.contributor.authorT. Shiodaen_US
dc.contributor.otherInstitute of Medical Science The University of Tokyoen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherTokyo Metropolitan Komagome Hospitalen_US
dc.date.accessioned2018-09-07T09:09:25Z-
dc.date.available2018-09-07T09:09:25Z-
dc.date.issued2000-01-01en_US
dc.identifier.citationGenes and Immunity. Vol.1, No.4 (2000), 293-294en_US
dc.identifier.issn14664879en_US
dc.identifier.other2-s2.0-0034577203en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034577203&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/25900-
dc.description.abstractInterleukin 16 (IL-16) is a chemotactic cytokine which binds to CD4 and affects T cell activation. Here we report a novel single nucleotide polymorphism, T to C, in the promoter region of the IL-16 gene in two distinct Asian populations, Japanese and Thai. This mutation occurs at an allele frequency of approximately 22% and 18%-respectively. Although IL-16 potently suppresses replication of human immunodeficiency virus type 1 (HIV-1), we observed no significant difference in the allele frequency of this polymorphism between HIV-1-infected and non-HIV-1-infected individuals in both Asian populations. Since differential IL-16 levels have been reported to be associated with inflammatory diseases such as systemic lupus erythematosus, atopic dermatitis and allergic asthma, it would be of interest to analyze the allele frequency of this mutation in patients with these autoimmune and allergic diseases.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034577203&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleA new polymorphism in the promoter region of the human interleukin-16 (IL-16) geneen_US
dc.typeArticleen_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1038/sj.gene.6363672en_US
Appears in Collections:Scopus 1991-2000

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.