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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/26229
Title: Erythrocyte antioxidant enzymes and blood pressure in relation to overweight and obese Thai in Bangkok
Authors: Duangkamol Viroonudomphol
Praneet Pongpaew
Rungsunn Tungtrongchitr
Benjaluck Phonrat
Venus Supawan
Niyomsri Vudhivai
Frank Peter Schelp
Mahidol University
Freie Universitat Berlin
Keywords: Medicine
Issue Date: 1-Jun-2000
Citation: Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.2 (2000), 325-334
Abstract: The specific activities of antioxidant enzymes, [eg superoxide dismutases (SOD), glutathione peroxidase (GPX) and catalase (CAT)], anthropometric measurements, including waist/hip ratio of 48 male and 167 female overweight persons (body mass index (BMI) ≥25.0 kg/m2) compared with a 26 male and 80 female control group (BMI = 18.5-24.9 kg/m2) of Thai volunteers who attended the Out-patient Department, General Practice Section, Rajvithi Hospital, Bangkok, for a physical check-up during March-October, 1998, were investigated. There was a slightly significant difference between the median age of the sexes. The medians of height, weight, and waist/hip ratio in males were significantly higher than those in female overweight and obese subjects. The median of arm circumference (AC), mid arm muscle circumference (MAMC) in males was significantly higher than those in female overweight and obese subjects (p < 0.05). The prevalences of hypertension based on systolic and diastolic blood pressure of ≥160/ ≥95 mmHg, were 8.3% and 37.5% for males and 5.4% and 18.6% for females, respectively. There was no significant difference between the median of antioxidant enzymes (SOD, GPX and CAT) between the sexes. No significant differences in the antioxidant enzymes in male overweight/obese persons and normal controls were presented, whereas antioxidant enzymes in female overweight/obese persons were statistically lower than in control females (p < 0.05). A significantly higher SOD, GPX, and CAT status was observed in normal subjects compared with overweight/obese subjects (p < 0.01). A higher prevalence of SOD ≤ 2,866 U/gHb, GPX (≤ 15.96 U/gHb in females was found, compared with males. A high percentage of lower catalase (CAT ≤ 19.2×104 ID/gHb) was found in both sexes (64.5% in males and 64.5% in females). In obese subjects (BMI ≥ 30.0 kg/m2), there were significantly positive relationships between systolic and diastolic blood pressure, systolic blood pressure and waist/hip ratio, and SOD could be related to weight, BMI as well as GPX and CAT, whereas the opposite result was observed for age and SOD.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034198385&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/26229
ISSN: 01251562
Appears in Collections:Scopus 1991-2000

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