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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/26280
Title: Disseminated infection due to rapidly growing mycobacteria in immunocompetent hosts presenting with chronic lymphadenopathy: A previously unrecognized clinical entity
Authors: Ploenchan Chetchotisakd
Piroon Mootsikapun
Siriluck Anunnatsiri
Kunya Jirarattanapochai
Charoen Choonhakarn
Angkana Chaiprasert
Preeyawis Na Ubol
L. Joseph Wheat
Thomas E. Davis
Khon Kaen University
Mahidol University
Indiana University School of Medicine Indianapolis
Keywords: Medicine
Issue Date: 7-Feb-2000
Citation: Clinical Infectious Diseases. Vol.30, No.1 (2000), 29-34
Abstract: Disseminated infection due to rapidly growing mycobacteria is uncommon and occurs mostly in immunocompromised patients. We report 16 cases of such infection with an unusual presentation seen at Srinagarind Hospital, a university hospital in northeastern Thailand. The clinical features were different from those in previous reports. All of the patients presented with chronic bilateral cervical lymphadenopathy. Twelve had mycobacterial involvement of other organs (sinuses, 6 patients; lungs, 4; liver, 4; spleen, 3; skin, 3; bone and joint, 2; and tonsils, 2). An interesting occurrence in 11 patients was 14 episodes of reactive skin manifestations (Sweet's syndrome, 9; generalized pustulosis and erythema nodosum, 2 each; and pustular psoriasis, 1). No identifiable predisposing factors, including human immunodeficiency disease, were found in these patients. However, 8 patients had 11 episodes of prior infection or coinfection with other opportunistic pathogens (salmonellosis, 4; penicilliosis, 3; pulmonary tuberculosis, 2; and melioidosis and cryptococcosis, 1 each). These findings suggest that cell- mediated immunity is defective in these patients.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0033956607&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/26280
ISSN: 10584838
Appears in Collections:Scopus 1991-2000

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