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Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/26789
Title: Effects of antileukotriene among asthmatic patients
Authors: Sawang Saenghirunvattana
Mahidol University
Keywords: Medicine
Issue Date: 1-May-2001
Citation: Journal of the Medical Association of Thailand. Vol.84, No.5 (2001), 719-722
Abstract: Study objective: To determine the effect of antileukotriene (montelukast) 10 mg once daily for the treatment of mild to moderate asthma. Design: Open label, prospective. Patients: Thirty asthmatic patients ≥18 years of age with baseline FEV1>60 per cent and ≤80 per cent of predicted values and evidence of reversible airway obstruction, as defined by an increase in FEV1 of ≥20 per cent. Interventions: Montelukast 10 mg once daily orally for 12 weeks, back up beta-2 agonist inhaler was available. Measurement and results: Spirometry was performed during the screening period, and every month after starting antileukotriene. Subjects recorded asthma-related symptoms and use of supplement beta-2 agonists daily on diary cards. Over 12 weeks of treatment, the FEV1 increased 10 per cent, 14 per cent and 19 per cent respectively, compared to the baseline (p<0.05). The physician and patients evaluation scores were quite good in the study. Conclusion: Oral montelukast once daily gave a favorable effect in management of mild to moderate asthmatic patients.
URI: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0034797814&origin=inward
http://repository.li.mahidol.ac.th/dspace/handle/123456789/26789
ISSN: 01252208
Appears in Collections:Scopus 2001-2005

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