Simple jQuery Dropdowns
Please use this identifier to cite or link to this item: http://repository.li.mahidol.ac.th/dspace/handle/123456789/27103
Full metadata record
DC FieldValueLanguage
dc.contributor.authorWalee Chamulitraten_US
dc.contributor.authorApsorn Sattayakhomen_US
dc.contributor.authorChristel Herold-Mendeden_US
dc.contributor.authorWolfgang Stremmelen_US
dc.contributor.otherUniversitat Heidelbergen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-09-13T06:20:47Z-
dc.date.available2018-09-13T06:20:47Z-
dc.date.issued2009-12-01en_US
dc.identifier.citationExperimental Dermatology. Vol.18, No.12 (2009), 1067-1069en_US
dc.identifier.issn16000625en_US
dc.identifier.issn09066705en_US
dc.identifier.other2-s2.0-70849100933en_US
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70849100933&origin=inwarden_US
dc.identifier.urihttp://repository.li.mahidol.ac.th/dspace/handle/123456789/27103-
dc.description.abstractEpithelial mesenchymal transition (EMT) has been implicated in neoplastic invasion and metastasis. We have previously generated six cell lines from human gingival mucosal keratinocytes immortalized by E6/E7 of human papillomavirus type 16. Ldk and NuB1 lines represented EMT phenotype and other four lines represented cobblestone non-EMT phenotype. These cell lines were utilized as model cells to determine whether inhibitors of apoptosis proteins and cell-cycle regulators were molecular players during EMT. EMT cells exhibited increased expression of vimentin, vascular endothelial growth factor (VEGF) receptor1 and the ability to form tubules on Matrigel as well as to grow anchorage independently. We found that EMT cells expressed significantly elevated levels of cIAP-1, Bclx and p27 kip higher than non-EMT cells. These proteins could therefore be used as intrinsic indicators of EMT of human gingival keratinocytes. © 2009 John Wiley & Sons A/S.en_US
dc.rightsMahidol Universityen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70849100933&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectMedicineen_US
dc.titleHuman papillomavirus 16 E6/E7-immortalized human gingival keratinocytes with epithelial mesenchymal transition acquire increased expression of cIAP-1, Bclx and p27Kip1en_US
dc.typeLetteren_US
dc.rights.holderSCOPUSen_US
dc.identifier.doi10.1111/j.1600-0625.2009.00888.xen_US
Appears in Collections:Scopus 2006-2010

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.