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Title: Deployment of innovative genetic vector control strategies: Progress on regulatory and biosafety aspects, capacity building and development of best-practice guidance
Authors: Camilla J. Beech
S. S. Vasan
M. Megan Quinlan
Margareth Lara Capurro
Luke Alphey
Vicente Bayard
Madama Bouaré
Maria Corena McLeod
Pattamaporn Kittayapong
James V. Lavery
Lee Han Lim
Mauro Toledo Marrelli
J. Nagaraju
Kenneth Ombongi
Rofina Yasmin Othman
Vilasini Pillai
Janine Ramsey
Rachel Reuben
Robert I. Rose
Brij Kishore Tyagi
John Mumford
Oxitec Limited
University of Oxford
Imperial College London
Universidade de Sao Paulo - USP
Gorgas Memorial Institute for Health Studies
University of Bamako
Mayo Clinic in Jacksonville, Florida
Mahidol University
Li Ka Shing Knowledge Institute
University of Toronto
Institute for Medical Research Kuala Lumpur
Centre for DNA Fingerprinting and Diagnostics India
University of Nairobi
University of Malaya
Kemeneterian Sains, Teknologi dan Inovasi
Kementerian Sumber Asli dan Alam Sekitar
Instituto Nacional de Salud Publica
Indian Council of Medical Research
Independent Biotechnology Consultant
Keywords: Biochemistry, Genetics and Molecular Biology
Issue Date: 1-Jan-2009
Citation: Asia-Pacific Journal of Molecular Biology and Biotechnology. Vol.17, No.3 (2009), 75-85
Abstract: In the ongoing fight against vectors of human diseases, disease endemic countries (DECs) may soon benefit from innovative control strategies involving modified insect vectors. For instance, three promising methods (viz. RIDL® [Release of Insects with a Dominant Lethal], Wolbachia infection, and refractory mosquito technology) are being developed by researchers around the world to combat Aedes aegypti, the primary mosquito vector of viral fevers such as dengue (serotypes 1-4), chikungunya and yellow fever. Some of these techniques are already being extended to other vectors such as Aedes albopictus (the secondary vector of these diseases) and Anopheles mosquito species that transmit malaria. To enable DECs to take advantage of these promising methods, initiatives are underway that relate to biosafety, risk assessment and management, and ethical-social-cultural (ESC) aspects to consider prior to and during the possible deployment of these technologies as part of an integrated vector control programme. This is a brief overview of the objectives and timelines of some of the initiatives being championed by international institutions, including the United Nations Development Programme (UNDP), the World Health Organization (WHO) and the Grand Challenges in Global Health (GCGH) initiative co-sponsored by the Bill & Melinda Gates Foundation.
ISSN: 01287451
Appears in Collections:Scopus 2006-2010

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