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Title: Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity
Authors: Nisachon Khunnawutmanotham
Nitirat Chimnoi
Arunee Thitithanyanont
Patchreenart Saparpakorn
Kiattawee Choowongkomon
Pornpan Pungpo
Supa Hannongbua
Supanna Techasakul
Chulabhorn Research Institute
Mahidol University
Kasetsart University
Ubon Rajathanee University
Keywords: Chemistry
Issue Date: 22-Jul-2009
Citation: Beilstein Journal of Organic Chemistry. Vol.5, (2009)
Abstract: Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wildtype and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT. © 2009 Khunnawutmanotham et al; licensee Beilstein-Institut.
ISSN: 18605397
Appears in Collections:Scopus 2006-2010

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